Prone to low acidity, Arneis should usually be consumed while fresh. The wine is also produced in a passito style from raisinated grapes. Prior to DOC regulation, this white grape was sometimes blended with Nebbiolo to temper the tannin and acidity of Barolo.

Arneis is a vigorous vine of potentially high productivity. It is best cultivated in chalky, sandy soils that lend it structure.

A native Piedmontese vine, Arneis originated in Roero. After approaching extinction in the early 1970s, Arneis was revived by a few producers in Piedmont who recognized its potential as a stand-alone variety.